Faculty180 - Vita and Individual Profile Data Sheet

Diana L Browning, PhD

Fall 1980 - Fall 2120

[email protected]

Current Position

Position: Adjunct Faculty

Biography

Dr. Diana Browning, PhD has had a continued human health focused career. In high school she learned about DNA and genetics which led her to attend the University of Coloardo at Boulder to study Molecular, Cellular, and Developmental Biology and Biochemistry. Here she first started doing laboratory related research and became interested in microbes and pathogens particularly viruses. After graduating with a BS in 2004, she persued a masters degree (2007) at Louisiana State State University Health Sciences Center in Virology and Immmunology where she developed more of an interest in all ascpects of pathogenesis and immunology. She then managed a project to investigate the affects of environmental contaminates on the adaptive immune system while training and working closly with undergraduate and graduate students. This experience was a driving force to return to graduate school in 2012 to persue a PhD in molecular biosciences from Washington State University (2016) working on combining her passions in science into a career in gene therapeutics and application strategies. She continues to work in gene therapy in Duarte, CA. Though her primary appointment does have her engage regularly in educating and training graduate students, interns, and new associates, she has a more formal interest in teaching and education. Diana Browning joined Southern California University Health Sciences Accelerated Sciences program as adjunct fuculty in Fall 2021.

Degrees

2016

Ph.D., Molecular Biosciences, Washington State University, Pullman, Washington, United StatesDissertation: Development of a Clinically Relevant Insulated Foamy Viral Vector for Hematopoietic Stem Cell Gene Therapy

2007

M.S., Virology and Immunology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United StatesDissertation: Chimeric Replicons and Vaccine Design: Practical Applications of Alphavirus Chimeric Technologies

2004

B.Sc., Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado, United States

Post-Graduate Training

Type: Post-Doctorate, City of Hope, Post-Doctorate, Gene Therapy, Duarte, California, United States, October 2016, October 2021

Work Experience

2021 - Ongoing

Staff Scientist, City of Hope, Duarte, California, United States

2008 - 2010

Laboratory Manager, University of Montana, Missoula, Montana, United States

Scholarly Contributions and Creative Productions

Journal Article

Completed/Published

Guan, Min, Laura Lim, Leo Holguin, Tianxu Han, Vibhuti Vyas, Ryan Urak, Aaron Miller, et al. 2022. “Pre-Clinical Data Supporting Immunotherapy for HIV Using CMV-HIV-Specific CAR T Cells with CMV Vaccine” 25:344–59.
Browning, D L., E M. Everson, D J. Leap, J D. Hocum, H Wang, G Stamatoyannopoulos, and G D. Trobridge. 2017. “Evidence for the in Vivo Safety of Insulated Foamy Viral Vectors” 24:187–98.
Browning, Diana L., and Grant D. Trobridge. 2016. “Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy” 4.
Browning, Diana L., Casey P. Collins, Jonah D. Hocum, David J. Leap, Dus T. Rae, and Grant D. Trobridge. 2016. “Insulated Foamy Viral Vectors” 27:255–66.
Rae, Dus T., Casey P. Collins, Jonah D. Hocum, Diana L. Browning, and Grant D. Trobridge. 2015. “Modified Genomic Sequencing PCR Using the MiSeq Platform to Identify Retroviral Integration Sites” 26:221–27.
Thueson, Lindsay E., Tiffany R. Emmons, Dianna L. Browning, Joanna M. Kreitinger, David M. Shepherd, and Scott A. Wetzel. 2015. “In Vitro Exposure to the Herbicide Atrazine Inhibits T Cell Activation, Proliferation, and Cytokine Production and Significantly Increases the Frequency of Foxp3+ Regulatory T Cells” 143:418–29.
Doherty, Melissa, Dou G. Osborne, Diana L. Browning, David C. Parker, and Scott A. Wetzel. 2010. “Anergic CD4+ T Cells Form Mature Immunological Synapses with Enhanced Accumulation of C-Cbl and Cbl-b” 184:3598–3608.