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Faculty

Faculty180 – Vita and Individual Profile Data Sheet

Daniel Handley, PhD, MS, BA

Fall 1980 - Fall 2120

Professor I

Human Genetics and Genomics Department

DanielHandley@scuhs.edu

Current Position

Position: Program Director, Master of Science in Genetics/Genomics

Biography

Dr. Handley serves as Founding Director of the Master of Science in Human Genetics and Genomics degree program at SCU. He also serves on the Board of Directors of Predictive Oncology, Inc. (NASDAQ: POAI) where he is chair of the Governance and Nomination Committee. Previously, he served as the Chief Scientific Officer of CTGRI in Florida and held a courtesy faculty appointment in the Department of Biological Sciences at Florida Gulf Coast University. He has served as the Chief Scientific Officer of Life-SEQ, LLC, a clinical genomic sequencing consulting company, as Chief Scientific Officer for Advanced Healthcare Technology Solutions, Inc., as a senior researcher at the Procter & Gamble Co., a senior administrator and laboratory manager at the David Geffen School of Medicine at UCLA, and as a founding technology innovator for the National Genetics Institute in Los Angeles, California.

Degrees

2008

M.S., Logic and Computation, Carnegie Mellon University, Pittsburgh, Pennsylvania, United StatesDissertation: Evaluating Machine Learning Algorithms Used to Infer Gene Regulatory Networks

Ph.D., Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United StatesDissertation: Systems Approach to Analyzing the TGF/SMAD3 Gene Regulatory Pathways in A549 Cells

1990

B.A., Biophysics, Johns Hopkins University, Baltimore, Maryland, United States

Post-Graduate Training

Type: Post-Doctorate, Magee-Womens Research Institute, Post-Doctorate, Genomics, Pittsburgh, Pennsylvania, United States, April 2008, April 2010

Work Experience

2015 - 2019

Courtesy Faculty, Florida Gulf Coast University, Fort Myers, Florida, United States

2013 - 2018

Chief Scientific Officer, Life-SEQ LLC, Bostom, Massachusetts, United States

2012 - 2019

Chief Scientific Officer, Clinical and Translational Genome Research Institute, Fort Myers, Florida, United States

2008 - 2013

Strategic Advisory Board Member, Brainstage, Inc., Pittsburgh, Pennsylvania, United States

1994 - 2000

Senior Research Associate, Procter and Gamble Company, Cincinnati, Ohio, United States

1991 - 1994

Laboratory Manager/Senior Administrative Analyst, UCLA School of Medicine, Los Angeles, California, United States

Scholarly Contributions and Creative Productions

Journal Article

Completed/Published

Ross, J. F.; Handley, D. E.; Fix, A. S.; Lawhorn, G. T.; Carr, G. J. Quantification of the Hindlimb Extensor Thrust Response in Rats. 19, 405–411.
Himes, K. P.; Handley, D.; Chu, T.; Burke, B.; Bunce, K.; Simhan, H. N.; Peters, D. G. Comprehensive Analysis of the Transcriptional Response of Human Decidual Cells to Lipopolysaccharide Stimulation. 2012, 93, 17–27.
Zhang, Y.; Handley, D.; Kaplan, T.; Yu, H.; Bais, A. S.; Richards, T.; Pandit, K. V.; Zeng, Q.; Benos, P. V.; Friedman, N.; Eickelberg, O.; Kaminski, N. High Throughput Determination of TGFβ1/SMAD3 Targets in A549 Lung Epithelial Cells. 2011, 6, e20319.
Rajakumar, A.; Chu, T.; Handley, D. E.; Bunce, K. D.; Burke, B.; Hubel, C. A.; Jeyabalan, A.; Peters, D. G. Maternal Gene Expression Profiling during Pregnancy and Preeclampsia in Human Peripheral Blood Mononuclear Cells. 2011, 32, 70–78.
Chu, T.; Handley, D.; Bunce, K.; Surti, U.; Hogge, W. A.; Peters, D. G. Structural and Regulatory Characterization of the Placental Epigenome at Its Maternal Interface. PloS one 2011, 6, e14723.
Pandit, K. V.; Corcoran, D.; Yousef, H.; Yarlagadda, M.; Tzouvelekis, A.; Gibson, K. F.; Konishi, K.; Yousem, S. A.; Singh, M.; Handley, D.; Richards, T.; Selman, M.; Watkins, S. C.; Pardo, A.; Ben-Yehudah, A.; Bouros, D.; Eickelberg, O.; Ray, P.; Benos, P. V.; Kaminski, N. Inhibition and Role of Let-7d in Idiopathic Pulmonary Fibrosis. American journal of respiratory and critical care medicine 2010, 182, 220–229.
Yu, H.; Königshoff, M.; Jayachandran, A.; Handley, D.; Seeger, W.; Kaminski, N.; Eickelberg, O. Transgelin Is a Direct Target of TGF-beta/Smad3-Dependent Epithelial Cell Migration in Lung Fibrosis. 2008, 22, 1778–1789.
Handley, D.; Serban, N.; Peters, D. G.; Glymour, C. Concerns about Unreliable Data from Spotted cDNA Microarrays due to Cross-Hybridization and Sequence Errors. Statistical applications in genetics and molecular biology 2004, 3, Article25.
Handley, D.; Serban, N.; Peters, D.; O’Doherty, R.; Field, M.; Wasserman, L.; Spirtes, P.; Scheines, R.; Glymour, C. Evidence of Systematic Expressed Sequence Tag IMAGE Clone Cross-Hybridization on cDNA Microarrays. 2004, 83, 1169–1175.
Handley, D. E.; Ross, J. F.; Carr, G. J. A Force Plate System for Measuring Low-Magnitude Reaction Forces in Small Laboratory Animals. 1998, 64, 661–669.
Schmid, P.; Conrad, A.; Syndulko, K.; Singer, E. J.; Handley, D.; Li, X.; Tao, G.; Fahy-Chandon, B.; Tourtellotte, W. W. W. Quantifying HIV-1 Proviral DNA Using the Polymerase Chain Reaction on Cerebrospinal Fluid and Blood of Seropositive Individuals with and without Neurologic Abnormalities. 1994, 7, 777–788.

Professional Membership

Spring 2020 - Ongoing

American Society of Human Genetics, January 2020, Ongoing

Summer 2021 - Ongoing

American Society for Microbiology, August 2021, Ongoing

Fall 2022 - Ongoing

American Association for the Advancement of Science, April 2015, Ongoing

Summer 2020 - Ongoing

Pharmacogenomics Global Research Network, July 2020, Ongoing, The mission of the Pharmacogenomics Global Research Network (PGRN) is to catalyze and lead research in precision medicine for the discovery and translation of genomic variation influencing therapeutic and adverse drug effects.

Hear from the Students Who’ve Been in Your Shoes

I chose SCU when looking for a PA program because of their Integrative Medicine approach. I am from Michigan, and not many programs focus on this Integrative, Holistic approach when it comes to patient care in the Midwest, and I felt that was very important for me to learn as a future provider. My transition to semi-virtual learning has been very smooth and quite enjoyable. [su_accordion][su_spoiler title="Read More..." open="No"]My favorite part about attending SCU is how tight-knit and diverse the community is. Coming from a large undergrad university and moving so far, it was very important for me to have a PA program that made me feel valued and invested in my success. At SCU, they do a great job of making you feel that.[/su_spoiler][/su_accordion]

Brianna Hadley

MSPA Class of 2022

One of the great things about SCU is we do have a campus layout, so all your classes aren't in a single room. We have our cadaver lab. We have different specialty rooms for physical assessment classes vs. acupuncture classes. All our acupuncture-specific classes have all the herbs in the room. You can pull out the herbs and look at them, whether in class or in between classes to get that extra studying in.[su_accordion][su_spoiler title="Read More..." open="No"]My favorite part of SCU is the collaboration from our beginning terms. We were working alongside chiropractor students, PA students, and ayurvedic students. It's a unique community where we get to learn about these different fields and sit in classrooms with them and work with them in the clinic. It allows you to get an understanding of all the different fields and how they can work together, and what is unique about your field. I think that is a wonderful aspect that I didn't think was going to be as prominent as it is here; even now, in my upper term classes and I am not in class with chiropractic students, I can still reach out to them about a certain aspect I may not understand or if I am working on a case. I want another perspective I know I have them to reach out to, so that has been a great networking community to have resources for.[/su_spoiler][/su_accordion]

 

Dr. Jamie Kuljis

Graduate, Doctor of Acupuncture and Chinese Medicine

"There are a lot of things that I love about the program at SCU. The first one is that the faculty come from a long line of Ayurvedic knowledge deeply rooted in ancient classical text. They studied Ayurveda, but they also lived it. When you learn from people who embody this wisdom, it's much easier to grasp this knowledge. The second thing I love is the camaraderie within the cohort. The combination of the training, supportive faculty, and the support of my peers and classmates has given me the confidence I need to start my own practice."

Portia Harris

Student, Ayurveda Program

Some of my favorite courses at SCU have to be the chiropractic procedure classes; those are the classes you get to hone in on your chiro skills, your palpation skills and ultimately work on the adjustments that make you a chiropractor. Those are the classes I feel enhance my knowledge the most and are some of the reasons I chose to become a chiropractor here are SCU.[su_accordion][su_spoiler title="Read More..." open="No"]On top of chiropractic procedures classes, my favorite is the cadaver lab experience. The cadaver classes opened up my perception of what the human body is made up of. It allowed me to get an in-person perspective of how the body works and looks on the inside. I am genuinely thankful for those experiences because they opened and broadened my horizons to the human body and anatomy in general.[/su_spoiler][/su_accordion]

 

Jordan Vega

Student, Doctor of Chiropractic

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